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Eye Health Over 50

Loss of vision is terrifying. Let's take control of our eye health with some simple actions critical for our aging eyes. Aging affects the eyes in multiple ways. Some of the most common conditions can lead to a gradual decline in our vision and, if ignored, can get worse...

I bought my first pair of readers when I was 43. I held out as long as I could. Within a few years, my friends and I were all comparing readers and prescriptions while perusing our dinner menus using the flashlights on our phones. Until then, I’d had the luxury of not paying any attention to eye health. Now, I have the luxury of receiving curated scientific studies from our AGEIST brand partners — like Timeline.

As we age, our bodies undergo a wide variety of changes (don’t we know it!), and our eyes are no exception. Maintaining eye health becomes increasingly crucial to ensure the quality of life and independence we all want. Let’s explore the aging process of the eyes, highlight the pivotal role of mitophagy, and discuss options we have to support our aging eyes.

Understanding Eye Health

Aging affects the eyes in multiple ways. Some of the most common conditions can lead to a gradual decline in our vision and, if ignored, can start to affect our ability to perform everyday tasks. 

  • Presbyopia – the difficulty of focusing on close objects
  • Cataracts  – the clouding of the lens
  • Glaucoma – damage to the optic nerve due to pressure
  • Age-related macular degeneration 
  • Diabetic retinopathy – damage to the retina due to diabetes

The Significance of Mitophagy in Eye Health

Mitophagy plays a critical role in the maintenance of cellular health and function by working to remove damaged mitochondria from the cell. Our mitochondria (the powerhouse of our cells) generate the energy needed for various cellular activities — yet, as mitochondria age or become damaged, they are a lot less efficient in doing their job. This is where mitophagy comes in. 

Mitophagy helps mitigate this damage by selectively degrading the dysfunctional mitochondria in order to maintain cellular health. In the context of eye health, mitophagy is especially important due to the high metabolic demand of visual processing, which requires optimal mitochondrial function.

Research shows that enhanced mitophagy can slow the progression of age-related eye diseases. By promoting mitophagy, it’s possible to remove damaged mitochondria, potentially slowing disease progression and preserving vision. Furthermore, studies suggest that interventions aiming to boost mitophagy could offer new therapeutic strategies for treating eye diseases associated with aging. 

Tips for Enhancing Mitophagy and Maintaining Eye Health

Current therapeutic strategies and tips include dietary approaches and pharmacological interventions designed to stimulate the mitophagy pathway. And, at AGEIST, we are big believers in addressing both the lifestyle changes that we can make and relying on scientific advancements to supplement our efforts. 

  • Regular Eye Exams: Early detection of eye conditions can prevent or slow down vision loss
  • Healthy Lifestyle: A balanced diet rich in vitamins and antioxidants, regular exercise, and avoiding smoking can support eye health
  • Eye Protection: Wearing sunglasses to protect against UV rays
  • Enhance Mitophagy: Urolithin A, a supplement known for stimulating mitophagy and preventing damaged mitochondria accumulation

Urolithin A was a hot topic in 2023 and, based on the effectiveness of the supplement, it will continue to rise in awareness and use. Getting the correct dosage is also key, which is why the AGEIST Scientific Board uses Mitopure. It’s a clinically validated, highly pure Urolithin A supplement proven to re-energize your cells and trigger mitophagy.

The more you know

We are all getting older — as are our eyes. But, understanding the role of mitophagy in maintaining cellular health presents new possibilities for mitigating age-related vision decline. By combining scientific advancements with practical health measures, we can better protect our eyes and maintain vision as we age. And, while my readers naturally transitioned into progressive lenses, I kinda love them. (And who doesn’t love an accessory with a purpose?) Timeline has a special discount for our readers (making it even easier to make those good, daily choices). Use code “AGEIST” at checkout and receive 10% off their products.

See medical disclaimer below. ↓


  1. Can you please direct me to research about Urolithin A and if it can help (or harm) someone who has wet macular degeneration. Thanks.


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The ideas expressed here are solely the opinions of the author and are not researched or verified by AGEIST LLC, or anyone associated with AGEIST LLC. This material should not be construed as medical advice or recommendation, it is for informational use only. We encourage all readers to discuss with your qualified practitioners the relevance of the application of any of these ideas to your life. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your physician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your physician or other qualified health provider. Please call your doctor or 911 immediately if you think you may have a medical or psychiatric emergency.

Ashley Feltner
Ashley is a writer, an artist, and an ideator who has placed storytelling into her process for bringing sales and marketing ideas to life for over 20 years. Her background includes recruiting, training, content development, and ERG leadership within highly matrixed organizations that provide her a unique perspective and an ability to authentically connect with individuals from all walks of life. With the desire to place a little humanity into the digital experience, Ashley believes that words do matter, a little empathy goes a long way, and having a purpose in life is imperative. She and her husband Gabe live in Nashville, TN with two very active teenage daughters and two very lazy field spaniels.

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