Studies have found that high-fat diets “can cause rapid changes in the bone marrow of mice, driving the production of inflammatory immune cells.” In fact, within 3 weeks, the mice experienced “metabolic disturbances throughout their body and in the bone marrow” where the fat cells in the bone marrow “multiply and take on white fat cell characteristics.” The production of inflammation can also contribute to “insulin resistance, type 2 diabetes and other complications in individuals with obesity.” The study concluded that “high-fat diets trigger a cascade of inflammation in the body that involves the bone marrow” and more research is needed to further understand the process and to investigate a way to prevent or reverse it.