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Molecule in Coffee Enhances Muscle Health

Researchers found that trigonelline, a natural molecule in coffee, fenugreek, and the human body, can enhance muscle health and function. Collaborating with multiple universities, they investigated sarcopenia, a condition where aging weakens muscles, leading to loss of mass and strength. The study revealed that declining levels of NAD+ and reduced mitochondrial activity contribute to sarcopenia, with older individuals showing lower trigonelline levels. Introducing trigonelline in pre-clinical models increased NAD+ levels and mitochondrial activity, and maintained muscle function. This discovery suggests the potential of trigonelline as a novel NAD+ precursor, offering promising interventions for healthy aging and age-related diseases alongside lifestyle recommendations like nutrition and physical activity.


See medical disclaimer below.

The ideas expressed here are solely the opinions of the author and are not researched or verified by AGEIST LLC, or anyone associated with AGEIST LLC. This material should not be construed as medical advice or recommendation, it is for informational use only. We encourage all readers to discuss with your qualified practitioners the relevance of the application of any of these ideas to your life. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your physician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your physician or other qualified health provider. Please call your doctor or 911 immediately if you think you may have a medical or psychiatric emergency.

Taylor Marks
Taylor Marks is a certified holistic health coach and professionally trained chef from The Institute of Culinary Education. Her passions include the latest research in health science, culinary arts, holistic wellness, and guiding others towards feeling their best.