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New Study: A Breakthrough in Longevity and Aging

The groundbreaking research of biotech firm Timeline and their promising compound, Mitopure, on aging in a recent clinical trial.

Timeline, a pioneering biotech firm at the front of longevity research, has achieved a significant milestone in its mission to develop interventions that could help people maintain their health for longer. The company recently unveiled the promising results of a landmark clinical trial investigating the effects of its proprietary compound, Mitopure, on immune aging. We have been taking Mitopure for two years now and, beyond how great it makes us feel, we appreciate Timeline’s commitment to vigorous testing. 

The MitoImmune Study

The study, dubbed MitoImmune, was a collaborative effort between Timeline and two prestigious research institutions: the Georg-Speyer-Haus Institute for Tumor and Experimental Therapy in Germany and the Buck Institute for Research on Aging in California. It was an intervention-based assessment of immune aging, involving 50 middle-aged adults who received a four-week regimen of either Mitopure or a placebo.

The trial’s primary objectives were twofold: to increase the number of youthful, naive CD8 T-cells, which play a crucial role in fighting infections and age-related diseases, and to improve the mitochondrial activity of these cells, which tends to decline with age. Remarkably, both of these primary endpoints were successfully met in the Mitopure group compared to the placebo group.

New Breakthroughs

“This is groundbreaking research that helps us better understand how we can counter the age-related decline of our immune system,” said Dr. Eric Verdin, CEO and President of the Buck Institute, hailing the study’s findings. “It shows us that we can rewire our body’s defense with targeted mitochondrial interventions like Mitopure.”

Dr. Dominic Denk, the Principal Investigator of the MitoImmune Study, echoed these sentiments, suggesting that the findings could have important implications for the oncology community.

Timeline’s Next Steps

Encouraged by these promising results, Timeline is now expanding its research efforts through collaborations with other esteemed institutions. In partnership with the National Institute of Aging, the company is launching a new clinical trial to investigate the impact of Mitopure on glucose metabolism in middle-aged overweight adults, potentially shedding light on its ability to improve metabolic health and mitigate age-related metabolic decline.

“Our mission has always been to pioneer research that unlocks clinically proven interventions to help people stay healthier for longer,” said Chris Rinsch, PhD, Co-Founder and President of Timeline. “These results open a totally new approach to directly impact our immune cells and help restore their functionality during aging.”

A Bright Future

Building on 15 years of research and multiple clinical studies, Timeline appears poised to make significant strides in the realm of longevity research, offering hope for interventions that could potentially extend human healthspan.

Timeline is giving AGEIST readers 10% off any plan with code “AGEIST” at checkout. 

See medical disclaimer below. ↓


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The ideas expressed here are solely the opinions of the author and are not researched or verified by AGEIST LLC, or anyone associated with AGEIST LLC. This material should not be construed as medical advice or recommendation, it is for informational use only. We encourage all readers to discuss with your qualified practitioners the relevance of the application of any of these ideas to your life. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your physician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your physician or other qualified health provider. Please call your doctor or 911 immediately if you think you may have a medical or psychiatric emergency.

Taylor Marks
Taylor Marks is a certified holistic health coach and professionally trained chef from The Institute of Culinary Education. Her passions include the latest research in health science, culinary arts, holistic wellness, and guiding others towards feeling their best.


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