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Can We Predict Time Until Death? Ryan Smith

What is the most impactful thing that most people can do to improve their chances of living longer? How does stress impact longevity? Could too much exercise have negative effects on our aging? Is time-restricted eating / intermittent fasting beneficial to longevity? 

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Ryan Smith, co-founder and vice president of business development at TruDiagnostic, joins us to discuss how his company is improving longevity by understanding our biological age vs chronological age, the different factors that accelerate or slow the aging process, and more.

“This idea of epigenetics is the on or off switches to your genes, controlling what actually gets expressed and then how those cells ultimately behave.” 

“People who are fast agers are, on average, 65% more likely to die than those who are average or slow agers.” 

“From an epidemiological perspective, there are a lot of things that I would recommend across the board and that is: getting proper sleep, making sure that you’re eating a healthy diet, making sure that you’re staying insulin sensitive and not insulin resistant.” 

“Working over 40 hours a week has been correlated to at least 1.5 years of additional age increase. The impact of stress has been one of those things that’s surprising in its effect size. It’s something that most people would consider as the main intervention for longevity.”

“Reducing stress is incredibly impactful.” 

“We know physical activity is impactful but it’s not the same effect size as things like BMI or stress.” 

Listen to the SuperAge podcast wherever you get your pods. 

Connect with Ryan Smith:

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The ideas expressed here are solely the opinions of the author and are not researched or verified by AGEIST LLC, or anyone associated with AGEIST LLC. This material should not be construed as medical advice or recommendation, it is for informational use only. We encourage all readers to discuss with your qualified practitioners the relevance of the application of any of these ideas to your life. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your physician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your physician or other qualified health provider. Please call your doctor or 911 immediately if you think you may have a medical or psychiatric emergency.


Taylor Marks
Taylor Marks is a certified holistic health coach and professionally trained chef from The Institute of Culinary Education. Her passions include the latest research in health science, culinary arts, holistic wellness, and guiding others towards feeling their best.


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