This study aimed to investigate the relationship between dietary patterns, specifically the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) and Mediterranean diets, and Alzheimer’s disease (AD) pathology. The researchers analyzed postmortem brain tissue from older adults who had completed a dietary questionnaire and had AD pathology data. The results showed that adherence to the MIND and Mediterranean diets was associated with lower global AD pathology and reduced β-amyloid load in the brain. These associations remained significant even after considering factors like age, sex, education, APOE-ε4 status, total calories, physical activity, smoking, and vascular disease burden. Additionally, higher intake of green leafy vegetables was specifically linked to less AD pathology.
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The Mediterranean Diet and Alzheimer’s Disease
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