Peter Attia of the Peter Attia Drive podcast is joined by Matt Kaeberlein, globally recognized researcher, to dive into the various definitions of aging, rapamycin, fasting, mTOR, and inflammation’s role in health and disease. They discuss the current state of the literature of testing rapamycin (and rapalogs) in animals and humans, including Matt’s Dog Aging Project, and provide insights into how we can improve future trials by conceptualizing risk, choosing better endpoints, and working with regulators to approve such trials. With new studies and research coming out about how we can effectively intervine in the aging process, it can be overwhelming. Matt leaves us with some wisdom: “I don’t think I will ever understand aging fully. And I don’t think the field will. … But I also believe that we don’t have to understand it fully to be able to have an impact on the biology of aging through interventions.” — Matt Kaeberlein
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The Biology of Aging, Rapamycin, and Other Interventions That Target the Aging Process.

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The ideas expressed here are solely the opinions of the author and are not researched or verified by AGEIST LLC, or anyone associated with AGEIST LLC. This material should not be construed as medical advice or recommendation, it is for informational use only. We encourage all readers to discuss with your qualified practitioners the relevance of the application of any of these ideas to your life. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your physician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your physician or other qualified health provider. Please call your doctor or 911 immediately if you think you may have a medical or psychiatric emergency.