The presence of senescent cells throughout the body is recognized as a contributing factor to the aging process. Given that senescent cells release various potentially harmful substances as part of the senescence-associated secretory phenotype (SASP), researchers in this study explored whether levels of selected SASP factors in circulation could forecast mortality among older individuals. They found that these biomarkers associated with cellular senescence enhanced the accuracy of mortality predictions beyond traditional demographic and clinical characteristics. The authors propose that “the circulating levels of these proteins might signify a fundamental mechanism of aging” and that “biomarkers reflecting cellular senescence serve as valuable predictors for significant health outcomes in older adults, including mortality.”
Welcome to Our Weekly Magazine
Become the best version of yourself Sign-up for our weekly magazine.
Become the best version of yourself today.
We send a weekly roundup of our best work and highlight standout community members. It's free, and you can always leave if it's not your jam.
Predicting Mortality With Specific Biomarkers
See medical disclaimer below.
The ideas expressed here are solely the opinions of the author and are not researched or verified by AGEIST LLC, or anyone associated with AGEIST LLC. This material should not be construed as medical advice or recommendation, it is for informational use only. We encourage all readers to discuss with your qualified practitioners the relevance of the application of any of these ideas to your life. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your physician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your physician or other qualified health provider. Please call your doctor or 911 immediately if you think you may have a medical or psychiatric emergency.