Predicting Mortality With Specific Biomarkers

Predicting Mortality With Specific Biomarkers

The presence of senescent cells throughout the body is recognized as a contributing factor to the aging process. Given that senescent cells release various potentially harmful substances as part of the senescence-associated secretory phenotype (SASP), researchers in this study explored whether levels of selected SASP factors in circulation could forecast mortality among older individuals. They found that these biomarkers associated with cellular senescence enhanced the accuracy of mortality predictions beyond traditional demographic and clinical characteristics. The authors propose that “the circulating levels of these proteins might signify a fundamental mechanism of aging” and that “biomarkers reflecting cellular senescence serve as valuable predictors for significant health outcomes in older adults, including mortality.”


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Taylor Marks is a certified holistic health coach and professionally trained chef from The Institute of Culinary Education. Her passions include the latest research in health science, culinary arts, holistic wellness, and guiding others towards feeling their best.