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Potential New Treatment for Diabetes

New groundbreaking research, published in Science Translational Medicine, reports on a therapeutic combination that regenerated human insulin-producing beta cells. This offers a potential new treatment for diabetes. Led by researchers from Mount Sinai Health System and City of Hope, the study combined harmine, a natural product found in some plants, with GLP1 receptor agonists. This resulted in a 700 percent increase in human beta cell numbers over three months in diabetic mice.

The study marks the first time scientists have developed a drug treatment proven to increase adult human beta cell numbers in vivo. Clearly, such results bring hope for future regenerative therapies for diabetes. Looking ahead, the research team has already completed a phase 1 clinical trial of harmine in healthy volunteers. They are also planning first-in-human trials with next-generation DYRK1A inhibitors next year. Additionally, researchers are exploring combining beta cell regeneration inducers with immunomodulators. This will address the immune system’s destruction of new beta cells in type 1 diabetes patients.

Study

See medical disclaimer below.

The ideas expressed here are solely the opinions of the author and are not researched or verified by AGEIST LLC, or anyone associated with AGEIST LLC. This material should not be construed as medical advice or recommendation, it is for informational use only. We encourage all readers to discuss with your qualified practitioners the relevance of the application of any of these ideas to your life. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your physician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your physician or other qualified health provider. Please call your doctor or 911 immediately if you think you may have a medical or psychiatric emergency.

Taylor Marks
Taylor Marks is a certified holistic health coach and professionally trained chef from The Institute of Culinary Education. Her passions include the latest research in health science, culinary arts, holistic wellness, and guiding others towards feeling their best.