Scientists have discovered that inhibiting the protein IL-11 can significantly extend the healthy lifespan of mice by up to 25%. In a study conducted by researchers from MRC LMS, Imperial College London, and Duke-NUS Medical School, mice treated with an anti-IL-11 antibody lived an average of 155 weeks compared to 120 weeks for untreated mice. The treatment reduced cancer deaths and diseases associated with aging, while improving muscle strength and overall health. IL-11 levels increase with age in both mice and humans, contributing to inflammation and hindering organ healing and regeneration. While these findings are promising, further research is needed to determine if similar effects can be achieved in humans and to establish the safety and effectiveness of anti-IL-11 treatments for aging-related conditions.
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Inhibiting This Protein Extends Healthspan of Mice. Are Human’s Next?

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