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Improving Crohn’s Outcomes

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Improving Crohn’s Outcomes

A clinical trial led by the University of Cambridge involving 386 newly-diagnosed Crohn’s disease patients demonstrated that initiating advanced therapy immediately after diagnosis greatly enhances outcomes, significantly reducing the need for urgent abdominal surgery by ten-fold. Despite the inability of a genetic biomarker to guide individual treatment selection, employing a ‘top-down” approach with infliximab yielded remarkable results, controlling symptoms and inflammation throughout the year-long trial period for 80% of patients, compared to 15% with the conventional ‘accelerated step-up’ strategy. Patients receiving early infliximab also exhibited higher rates of endoscopic remission, better quality of life, decreased steroid use, and fewer hospitalizations, with only 0.5% requiring urgent surgery compared to 5% in the conventional treatment group. The findings challenge previous notions of ‘early’ treatment and advocate for immediate intervention upon diagnosis to prevent disease progression and improve patient outcomes, potentially revolutionizing standard clinical care for Crohn’s disease.

Study

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The ideas expressed here are solely the opinions of the author and are not researched or verified by AGEIST LLC, or anyone associated with AGEIST LLC. This material should not be construed as medical advice or recommendation, it is for informational use only. We encourage all readers to discuss with your qualified practitioners the relevance of the application of any of these ideas to your life. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your physician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your physician or other qualified health provider. Please call your doctor or 911 immediately if you think you may have a medical or psychiatric emergency.

Taylor Marks is a certified holistic health coach and professionally trained chef from The Institute of Culinary Education. Her passions include the latest research in health science, culinary arts, holistic wellness, and guiding others towards feeling their best.
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