A study published in Nature investigated the relationship between exercise, obesity, type 2 diabetes, and other cardiometabolic diseases. The study found that “exercise stimulates the production of N-lactoyl-phenylalanine (Lac-Phe), a blood-borne signalling metabolite that suppresses feeding and obesity.” In mice studies, obese mice were given Lac-Phe and the researchers found that it reduced “food intake without affecting movement or energy expenditure.” The discovery that exercise stimulates the production of Lac-Phe is an important one because it allows us to better understand the full effects of exercise, particularly its effects on our appetite and obesity.