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Breakthrough in Understanding Inflammatory Bowel Disease (IBD)

In a groundbreaking study, researchers from the United Kingdom identified a major cause of inflammatory bowel disease (IBD), which encompasses Crohn’s disease and ulcerative colitis. The global prevalence of these autoimmune conditions has been on the rise, with an estimated 6.8 million people affected in 2017, up from 3.7 million in 1990, making new discoveries about their origins increasingly crucial. The research, conducted at the Francis Crick Institute in London, revolves around a gene called ETS2 and its associated “enhancer” section of DNA that boosts its expression, with higher levels of ETS2 correlating to an increased risk of developing IBD. The findings also confirm the involvement of other genes previously linked to the disease, as they are part of the ETS2 pathway. Lead researcher James Lee described the discovery as a significant breakthrough, stating, “What we have found is one of the very central pathways that goes wrong when people get inflammatory bowel disease and this has been something of a holy grail.”


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The ideas expressed here are solely the opinions of the author and are not researched or verified by AGEIST LLC, or anyone associated with AGEIST LLC. This material should not be construed as medical advice or recommendation, it is for informational use only. We encourage all readers to discuss with your qualified practitioners the relevance of the application of any of these ideas to your life. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your physician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your physician or other qualified health provider. Please call your doctor or 911 immediately if you think you may have a medical or psychiatric emergency.

Taylor Marks
Taylor Marks is a certified holistic health coach and professionally trained chef from The Institute of Culinary Education. Her passions include the latest research in health science, culinary arts, holistic wellness, and guiding others towards feeling their best.