A study presented at the European Academy of Neurology Congress found that a simple blood test measuring insulin resistance can predict rapid cognitive decline in early Alzheimer’s disease. Researchers analyzed 315 non-diabetic patients with neurodegenerative conditions, using the triglyceride-glucose (TyG) index as a marker of insulin resistance. Among 161 patients with mild cognitive impairment due to Alzheimer’s disease, those with the highest TyG levels were over four times more likely to experience rapid cognitive decline, losing more than 2.5 points per year on cognitive tests. This predictive relationship was specific to Alzheimer’s patients and was not observed in those with other neurodegenerative diseases. These findings suggest that this widely available, low-cost blood test could help clinicians identify Alzheimer’s patients at higher risk of rapid deterioration, enabling more targeted interventions and treatment planning.
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Blood Test to Predict Rapid Cognitive Decline in Early Alzheimer’s Disease
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The ideas expressed here are solely the opinions of the author and are not researched or verified by AGEIST LLC, or anyone associated with AGEIST LLC. This material should not be construed as medical advice or recommendation, it is for informational use only. We encourage all readers to discuss with your qualified practitioners the relevance of the application of any of these ideas to your life. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your physician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your physician or other qualified health provider. Please call your doctor or 911 immediately if you think you may have a medical or psychiatric emergency.