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Sensitive to Retinol? Discover OneSkin’s Gentle Solution for Aging Skin

While retinol is hailed as the gold standard in skincare for aging and changing skin, it can be problematic for those with sensitive skin. Enter OneSkin. From peptide power for skin renewal to providing deep hydration and barrier support, OneSkin can help you get powerful retinol-like results without the irritation. (In collaboration with OneSkin.)

Calling all sensitive skin types. Maintaining glowy and healthy skin is great for our confidence as we age. Fine lines, wrinkles, and the natural decline in collagen production are inevitable, so being the best version of ourselves at every age and stage is the ultimate mission.

For those in the know, retinol is hailed as the gold standard in skincare for aging and changing skin. But what happens when your skin can’t handle it? You’re not alone if you’ve experienced redness, irritation, or sensitivity from retinol. Thankfully, OneSkin is revolutionizing the anti-aging game with a potent skin renewal solution without harsh side effects. Leveraging cutting-edge science, OneSkin’s formulas work deep at the cellular level, making them ideal for those sensitive to retinol. 

The Problem with Retinol for Sensitive Skin

Retinol, a vitamin A derivative, is renowned for increasing cell turnover, boosting collagen production, and minimizing fine lines. But it often comes with side effects like dryness, peeling, irritation, and increased sensitivity to sunlight, especially when first introduced to the skin. These negative effects are usually short-lived; however, they can persist far beyond the normal adaptation period for those with sensitive or reactive skin. The issue lies in how retinol accelerates cell turnover.

The rapid shedding of skin cells can temporarily weaken your skin barrier, leaving your skin vulnerable to further sensitivity and dryness. If you already have sensitive skin, this can lead to a vicious cycle of water loss, redness, and flakiness as you try to push through and continue using retinol. This makes it challenging for people with sensitive skin to benefit from retinol without enduring uncomfortable short-term, or potentially longer-term, consequences. 

Enter OneSkin: Science-Backed, Skin-Friendly Solutions

OneSkin provides a refreshing alternative for those who’ve struggled with retinol. Instead of relying on vitamin A derivatives, OneSkin’s OS-01 formulas employ the OS-01 peptide, which is scientifically proven to promote key biomarkers associated with collagen and hyaluronic acid production and increase skin’s epidermal thickness.1 Plus, they’re packed with other advanced ingredients designed to promote skin health at a cellular level. 

If you love retinol, you can still use it with OneSkin by alternating OS-01 FACE and retinol. In fact, OneSkin’s topical supplements may help counteract the temporary negative effects of retinol by helping to build back the skin barrier that retinol temporarily degrades. Apply retinol at night and OS-01 FACE in the morning to enjoy both benefits. You can also combine them in the same routine. After cleansing, apply OS-01 FACE first for maximum peptide absorption. As mentioned, OS-01 FACE helps counteract retinol’s harsh side effects, but if you’re sensitive to retinol, skip it and stick with just OS-01 FACE. It offers similar benefits without the drawbacks. 

Peptide Power for Skin Renewal

The OS-01 peptide is the linchpin of OneSkin’s formulas. This patented peptide rejuvenates your skin by supporting cellular health and enhancing the skin’s barrier function. Unlike retinol, the OS-01 peptide works harmoniously with your skin’s natural processes to help the skin behave like its younger self. It does this without compromising your skin’s hydration or inducing irritation or redness. 

Deep Hydration and Barrier Support

One critical issue with retinol is that it temporarily compromises the skin’s moisture barrier, thereby leading to dryness and peeling. OneSkin’s OS-01 FACE formula takes a different approach, actively supporting hydration and building up barrier function.1 Ingredients like hyaluronic acid and glycerin lock in moisture, ensuring your skin remains supple and protected throughout the day. 

Targets Senescent Cells

OneSkin’s innovation extends far beyond mere hydration. The formula targets senescent cells—aged cells that no longer function optimally but haven’t yet died off. By reducing these cells, OneSkin enhances your skin’s efficiency, improving its overall appearance and texture without stressing the skin’s surface. This gentle process is ideal for sensitive skin types. 

Retinol-Like Benefits Without the Sensitivity

The OS-01 FACE formula delivers anti-aging results akin to retinol—improved skin elasticity, reduced wrinkles, and a smoother complexion1—without irritation. Additionally, OneSkin’s scientists have found that both retinol and OS-01 FACE increase key biomarkers associated with collagen production and cellular turnover at similar levels. Plus, OS-01 FACE promotes a significant increase in epidermal thickness, a commonly cited benefit of retinol.1 Its slow, steady support ensures your skin’s natural functions improve texture and firmness,1 even if you’ve previously struggled with retinol. 

Unlike retinol, which often requires a cautious introduction and strict application schedule due to the risk of over-exfoliating, OneSkin is gentle enough for daily use. This consistency allows for better results over time without the fear of exacerbating sensitivity. 

Why OneSkin Is “the One”

Skin sensitivity can become more common as we age, particularly for those over 50. As the skin naturally thins and becomes more reactive, prioritizing skin longevity and wellness requires a scientifically validated product that delivers results without compromising skin health. OneSkin meets that demand by addressing deeper cellular aspects of aging, ensuring your skin remains resilient and radiant despite sensitivity. 

A Personalized Approach to Aging

At OneSkin, the focus isn’t merely on reducing wrinkles but on optimizing skin health from within. This holistic approach aligns perfectly with thriving in midlife and beyond. By offering a safe, effective, and skin-friendly formula, OneSkin empowers those with sensitive skin to age confidently. 

The Takeaway

If you’ve hesitated to try retinol due to adverse reactions, consider a more thoughtful alternative. OneSkin’s innovative, science-backed formulas offer the benefits of potent anti-aging ingredients without irritation. Take control of your skin’s future with a product designed to help you and your sensitive skin age beautifully. 

Besides the glowing results we saw in the mirror, we found OneSkin’s comprehensive approach to aging intriguing. They don’t just focus on the superficial signs of aging; instead, they tackle it from the cellular level, ensuring that even the most sensitive skin can enjoy the journey to resilience and radiance. It’s more than skincare; it’s skin intelligence.

Are you skin sensitive or just looking for a retinol alternative? Get smart and make the switch to a streamlined, science-driven skincare routine. For new customers, enjoy 15% off your first purchase with the exclusive code AGEIST15.

 1 Based on data from clinical studies and/or lab studies conducted on human skin samples, models, and cells in the OneSkin lab. Explore more at oneskin.co/claims.

Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. Npj Aging, 9(1), 1-15. 2023.

Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024.

See medical disclaimer below. ↓

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The ideas expressed here are solely the opinions of the author and are not researched or verified by AGEIST LLC, or anyone associated with AGEIST LLC. This material should not be construed as medical advice or recommendation, it is for informational use only. We encourage all readers to discuss with your qualified practitioners the relevance of the application of any of these ideas to your life. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your physician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your physician or other qualified health provider. Please call your doctor or 911 immediately if you think you may have a medical or psychiatric emergency.

Sheri Radel Rosenberghttps://unapologeticstyle.substack.com/
Sheri Radel Rosenberg is a Philly-born, Brooklyn-based writer who explores style, beauty, culture, and midlife with wit, warmth, and wisdom. Her story includes successful forays in the worlds of trend forecasting, ad agency photo production, ghostwriting, and strategic messaging development for fashion and beauty brands - all while amassing a slip dress collection that would make any Gen Xer proud. At the dawn of social media, Sheri launched her personal blog–which combines her passion for writing with her style obsession–and she hasn’t looked back. As Style Editor for the AGEIST, she’s inspired by the styles of the 70s and the 90s, along with all the beautiful people she sees daily in NYC.

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