What if AI could analyze your health data and tell you exactly what to do to live longer? Guy Leitersdorf, CEO of Longevity AI, joins us to explain how his platform uses real-time biomarkers, behavioral science, and AI to optimize health decisions. Instead of one-size-fits-all advice, Longevity AI acts as a personal health coach, adjusting its guidance based on your habits, preferences, and biological markers. On this week’s episode of The AGEIST Podcast, we discuss the five key aging conditions, the role of real-time health nudges, and how AI-powered insights can help physicians move from reactive care to true preventative medicine.
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Key Moments
“Nobody likes to treat their health as a chore, so we match habits to what people actually want to do.”
“Physicians don’t have time to analyze every piece of data—AI can harmonize it all and provide real-time, personalized insights.”
“The question isn’t just what you can do to improve your health, it’s what you will do—and that’s where behavioral science comes in.”
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The Rise of AI in Personalized Health
Preventative medicine has long been an aspiration rather than a reality. Most people only seek medical advice when something goes wrong, and even the best physicians struggle to synthesize massive amounts of patient data. Guy Leitersdorf’s Longevity AI is attempting to change that by bringing artificial intelligence into the heart of personalized healthcare.
Unlike traditional health tracking apps, Longevity AI aggregates real-time biometrics—including blood tests, genetics, wearables, and lifestyle data—and applies advanced behavioral science to create actionable recommendations. Leitersdorf describes it as “a copilot, a friend, a coach” that delivers real-time nudges tailored to what each user is actually willing to do.
Targeting the Five Horsemen of Aging
The core focus of Longevity AI is addressing what Leitersdorf calls the “Five Horsemen” of aging: cardiovascular disease, diabetes, cancer, dementia, and metabolic disorders. With access to longitudinal health records from 1.6 million people, the AI can predict individual risks and suggest interventions long before symptoms appear.
For example, if an individual’s heart health is declining, the AI might suggest a targeted exercise regimen rather than a generic fitness plan. It adapts based on behavioral responses—some users might receive a push notification, others an email, depending on their preferences. The system continuously refines its approach to maximize engagement and adherence.
A New Role for AI in Medicine
Physicians today are often overwhelmed with fragmented patient data. Longevity AI acts as an integrator, “harmonizing all their service providers, from running apps to genetic reports,” Leitersdorf explains. Rather than replacing doctors, the AI enhances their ability to deliver data-driven, preventative care in less time.
In a world where most medical visits still focus on treating illness rather than optimizing health, Longevity AI offers a glimpse into a future where AI-powered coaching becomes a daily part of longevity strategy. As Leitersdorf puts it, “We’re not just telling you what you should do—we’re making it easy for you to actually do it.”
For more on Guy Leitendorf’s insights and Longevity AI, listen to his full interview on The AGEIST Podcast and/or check out the full episode transcript.
The ideas expressed here are solely the opinions of the author and are not researched or verified by AGEIST LLC, or anyone associated with AGEIST LLC. This material should not be construed as medical advice or recommendation, it is for informational use only. We encourage all readers to discuss with your qualified practitioners the relevance of the application of any of these ideas to your life. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your physician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your physician or other qualified health provider. Please call your doctor or 911 immediately if you think you may have a medical or psychiatric emergency.
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