Dr. Paul Kolodzik spent 25 years in emergency medicine watching the long-term consequences of preventable disease. Now, he’s helping patients reverse metabolic syndrome using continuous glucose monitors (CGMs), low-carb nutrition, and strength training. In this episode of The AGEIST Podcast, Dr. Kolodzik explains why blood sugar spikes—not cholesterol—may be the most urgent threat to long-term health. You’ll also hear why he believes wearables and strategic use of GLP-1 medications can radically change your health trajectory.
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Key Moments
“Fatty liver disease isn’t from eating too much fat—it’s, for most people, excessive carb intake.”
“Once I see it, I can’t unsee it. And then you know what’s going on with your blood sugar physiology.”
“Strength training reverses insulin resistance. Your muscles are soaking up more insulin and more blood glucose.”
Connect With Dr. Paul Kolodzik
Book: The Continuous Glucose Monitor Revolution for Non-Diabetics
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Metabolic Syndrome: A Preventable Health Crisis
Dr. Paul Kolodzik spent decades treating heart attacks, strokes, and diabetic complications in the ER. But what he saw time and again wasn’t just trauma—it was preventable illness tied directly to metabolic dysfunction. In his interview on The AGEIST Podcast, Dr. Kolodzik makes a strong case for why continuous glucose monitoring (CGM) isn’t just for diabetics—it’s a tool for anyone serious about their long-term health.
Controlling Blood Glucose for Long-Term Health
Dr. Kolodzik, now a metabolic health physician, believes that controlling blood glucose is the key to preventing diseases like Alzheimer’s, heart disease, and kidney failure. He explains that even short spikes in blood sugar can trigger damaging inflammation in blood vessels. “This is why diabetics have [a] much higher risk of dementia or Alzheimer’s disease than people [who] are not diabetic,” he says. Dr. Kolodzik also highlights how the shift away from traditional calorie-counting diets to more sustainable strategies, which include low-carb nutrition, intermittent fasting, and strength training, can help—and his approach is data-driven.
Patients begin with a CGM to track their real-time glucose responses. From there, they’re guided toward lifestyle changes—often starting with reducing carbohydrates to below 75 grams per day. From Dr. Kolodzik’s experience, CGMs can shift a person’s relationship with food because the wearable allows them to see the spikes caused by everyday meals. “Once I see it, I can’t unsee it,” his patients often tell him.
GLP-1s and Long-Term Health
Along with talking about blood sugar spikes and the importance of regulating them, Dr. Kolodzik also addresses the current explosion of interest in GLP-1 drugs like Ozempic and Monjaro. While he sees their utility, he cautions against long-term use without a supporting lifestyle plan. “These medicines lower blood sugar, but they also lower muscle mass,” he warns. His method favors lower doses for short durations, always paired with diet and exercise, particularly strength training to improve insulin sensitivity.
Actionable Data for Positive Change
If you’re interested in staying strong, mobile, and metabolically stable well into your later years, this conversation is essential listening. From understanding your A1C levels to learning why orange juice might be sabotaging your morning, Dr. Kolodzik offers practical advice about diet, exercise, and more. His grounded, clinical insights offer a roadmap for anyone looking to take health into their own hands—one data point at a time.
Tune in to hear more of Dr. Paul Kolodzik’s insights on The AGEIST Podcast or check out the full interview transcript.
The ideas expressed here are solely the opinions of the author and are not researched or verified by AGEIST LLC, or anyone associated with AGEIST LLC. This material should not be construed as medical advice or recommendation, it is for informational use only. We encourage all readers to discuss with your qualified practitioners the relevance of the application of any of these ideas to your life. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your physician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your physician or other qualified health provider. Please call your doctor or 911 immediately if you think you may have a medical or psychiatric emergency.
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